vxzbcmn , I suggest exercising when you start taking it because the weight will come off even if you do nothing, and that can be deceiving in that you won't think you have to work as hard and you'll gain it back plus some when you stop. vxzbcmnm , Administration of methylphenidate (20 mg/day) during days 22-28 of modafinil treatment 8 hours after the daily dose of modafinil did not cause any significant alterations in the pharmacokinetics of modafinil. vxzbcmnm , Other measures to detoxify the gut include administration of activated charcoal and a cathartic. vxzbcmnm , Because many drugs are excreted in human milk, caution should be exercised if Concerta? is administered to a nursing woman. vxzbcmnm , Chronic administration of modafinil can increase the elimination of substrates of CYP3A4. vxzbcmnm , You really have to put your foot down and be ready to lose the weight and keep it off. vxzbcmnm , If Provigil is used adjunctively with CPAP, the encouragement of and periodic assessment of CPAP compliance is necessary.